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BDBM340041 2-(5-Methoxy-2-methyl-2H-indazol-3-yl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid::US9758517, Example 2

SMILES: COc1ccc2nn(C)c(-c3cc4nccc(C(O)=O)c4[nH]3)c2c1

InChI Key: InChIKey=AOVIOXUIFLZHIH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340041   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 4C (JMJD2C)


(Homo sapiens (Human))
BDBM340041
PNG
(2-(5-Methoxy-2-methyl-2H-indazol-3-yl)-1H-pyrrolo[...)
Show SMILES COc1ccc2nn(C)c(-c3cc4nccc(C(O)=O)c4[nH]3)c2c1
Show InChI InChI=1S/C17H14N4O3/c1-21-16(11-7-9(24-2)3-4-12(11)20-21)14-8-13-15(19-14)10(17(22)23)5-6-18-13/h3-8,19H,1-2H3,(H,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9758517 (2017)

More data for this
Ligand-Target Pair