BDBM340063 2-fluoro-4-{5-(4-methylphenyl)-8-[(3R)-pyrrolidin-3-ylmethoxy][1,2,4]triazolo[4,3-a]pyridin-6-yl}benzonitrile::US9758523, Example 2

SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCN(C2)C(=O)OC(C)(C)C)c2nncn12)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=LMOZZLPNNRZMMC-HXUWFJFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340063   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM340063(2-fluoro-4-{5-(4-methylphenyl)-8-[(3R)-pyrrolidin-...)
Affinity DataIC50: <50nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent