BDBM340274 (1R,3S,5R)-2-(2-(4- bromo-3-carbamoyl- 1H-pyrazol-1- yl)acetyl)-N-(2'-chloro- 2-fluorobiphenyl-3-yl)-2- azabicyclo[3.1.0]hexane- 3-carboxamide::US9758537, Compound 77

SMILES NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(c2F)-c2ccccc2Cl)cc1Br

InChI Key InChIKey=MNGCWVCWHPIDOP-DPMMWBKBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340274   

TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM340274((1R,3S,5R)-2-(2-(4- bromo-3-carbamoyl- 1H-pyrazol-...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent