BDBM340323 (Scheme B): Preparation of methyl (3S)-3-{[4-(2-aminopyrimidin-5-yl)-6-(morpholin-4-yl)-1,3,5-triazin-2-yl]amino}-3-(hydroxymethyl)pyrrolidine-1-carboxylate::US9758538, Example 11
SMILES COC(=O)N1CC[C@@](CO)(C1)Nc1nc(nc(n1)-c1cnc(N)nc1)N1CCOCC1
InChI Key InChIKey=HARVFSFQZNBQEZ-SFHVURJKSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 340323
Affinity DataKi: 0.103nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85...More data for this Ligand-Target Pair