BDBM340323 (Scheme B): Preparation of methyl (3S)-3-{[4-(2-aminopyrimidin-5-yl)-6-(morpholin-4-yl)-1,3,5-triazin-2-yl]amino}-3-(hydroxymethyl)pyrrolidine-1-carboxylate::US9758538, Example 11

SMILES COC(=O)N1CC[C@@](CO)(C1)Nc1nc(nc(n1)-c1cnc(N)nc1)N1CCOCC1

InChI Key InChIKey=HARVFSFQZNBQEZ-SFHVURJKSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340323   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM340323((Scheme B): Preparation of methyl (3S)-3-{[4-(2-am...)
Affinity DataKi:  0.103nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent