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BDBM340333 US9758538, Example 21

SMILES: C[C@H]1COCCN1c1nc(N[C@@]2(C)CCN(C2)C(C)=O)cc(n1)-c1cnc(N)nc1

InChI Key: InChIKey=YBEGUSZLSLVGRW-RBZFPXEDSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340333   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase regulatory subunit alpha


(Homo sapiens (Human))
BDBM340333
PNG
(US9758538, Example 21)
Show SMILES C[C@H]1COCCN1c1nc(N[C@@]2(C)CCN(C2)C(C)=O)cc(n1)-c1cnc(N)nc1
Show InChI InChI=1S/C20H28N8O2/c1-13-11-30-7-6-28(13)19-24-16(15-9-22-18(21)23-10-15)8-17(25-19)26-20(3)4-5-27(12-20)14(2)29/h8-10,13H,4-7,11-12H2,1-3H3,(H2,21,22,23)(H,24,25,26)/t13-,20-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
0.605n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...


US Patent US9758538 (2017)

More data for this
Ligand-Target Pair