BDBM340396 US9758538, Example 84

SMILES CN1CCCC(N2CC[C@@](CO)(C2)Nc2cc(nc(n2)N2CCOCC2)-c2cnc(N)nc2)C1=O

InChI Key InChIKey=OEMLRFQWNLYLBJ-IMMUGOHXSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340396   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM340396(US9758538, Example 84)
Affinity DataKi:  0.445nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent