BDBM340451 US9758538, Example 141

SMILES Nc1ncc(cn1)-c1cc(N[C@@]2(CO)CCCN(C2)C(=O)OCC(F)F)nc(n1)N1CCOCC1

InChI Key InChIKey=VGAVWMNMADPYAM-NRFANRHFSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340451   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM340451(US9758538, Example 141)
Affinity DataKi:  0.0430nMAssay Description:The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent