BDBM340545 US9763922, Example 76

SMILES CCC(O)c1cccc(c1)-c1cccc(Nc2nn(CC3CC3)c3CCN(Cc23)C(C)=O)c1

InChI Key InChIKey=COHJFFNOXQFYOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340545   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM340545(US9763922, Example 76)
Affinity DataIC50:  900nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM340545(US9763922, Example 76)
Affinity DataIC50:  10nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent