BDBM340659 1-[3-[4-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]anilino]-1-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone::US9763922, Example 186

SMILES CN(C)CCn1cc(cn1)-c1ccc(Nc2nn(C)c3CCN(Cc23)C(C)=O)cc1

InChI Key InChIKey=IEKLIPQVNVOPET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340659   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM340659(1-[3-[4-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]an...)
Affinity DataIC50:  6.75E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM340659(1-[3-[4-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]an...)
Affinity DataIC50:  120nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent