BDBM340742 US9763922, Example 268

SMILES CNC(=O)N1CCc2c(C1)c(Nc1cc(F)c(cc1F)-c1cnn(C)c1)nn2C1CCOCC1

InChI Key InChIKey=LYAFLLPZNCVTCT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340742   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM340742(US9763922, Example 268)
Affinity DataIC50:  1.22E+4nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM340742(US9763922, Example 268)
Affinity DataIC50:  4nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent