BDBM340822 US9765040, Compound 14

SMILES CC(C)(Oc1ccc(F)cc1F)c1nnc(-c2ccc(cc2Cl)C(N)=O)n1C1CC1

InChI Key InChIKey=VFZZAKDTAULXIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340822   

Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Astellas Pharma

US Patent
LigandPNGBDBM340822(US9765040, Compound 14)
Affinity DataIC50:  16nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent