BDBM340834 US9765018, Example 287

SMILES CCCC(CCC)Oc1c(Br)cc(cc1NC(=O)Nc1ccccc1F)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=RCDIDCDPBBVKLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340834   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM340834(US9765018, Example 287)
Affinity DataIC50:  3nMAssay Description:Inhibition of human IDO1 in HEK293 cells after 20 hrs by plate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM340834(US9765018, Example 287)
Affinity DataIC50:  4.49nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent