BDBM341049 1-(5-Bromo-2-{[(3S)-3-[(4-methylpiperazin-1-yl)carbonyl]-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}phenyl)-N-(4-hydroxyphenyl)-N-(1H-indol-5-yl)-5-methyl-1H-pyrrole-3-carboxamide::US9765056, Example 101

SMILES CN1CCN(CC1)C(=O)[C@@H]1Cc2ccccc2CN1C(=O)c1ccc(Br)cc1-n1cc(cc1C)C(=O)N(c1ccc(O)cc1)c1ccc2[nH]ccc2c1

InChI Key InChIKey=GUTLWLPHRGSJCV-KDXMTYKHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341049   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
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US Patent
LigandPNGBDBM341049(1-(5-Bromo-2-{[(3S)-3-[(4-methylpiperazin-1-yl)car...)
Affinity DataIC50:  99.1nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent