BDBM341050 1-(5-Bromo-2-{[(3S)-3-[(4-cyclobutylpiperazin-1-yl)methyl]-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}phenyl)-N-(4-hydroxyphenyl)-N-(1H-indol-5-yl)-5-methyl-1H-pyrrole-3-carboxamide::US9765056, Example 102
SMILES Cc1cc(cn1-c1cc(Br)ccc1C(=O)N1Cc2ccccc2C[C@H]1CN1CCN(CC1)C1CCC1)C(=O)N(c1ccc(O)cc1)c1ccc2[nH]ccc2c1
InChI Key InChIKey=RJTYCCFHPWDWDX-KDXMTYKHSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 341050
Affinity DataIC50: 8.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair