BDBM341060 N-(4-Hydroxyphenyl)-1-(6-{[(3S)-3-(morpholin-4-ylmethyl)-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}-1,3-benzodioxol-5-yl)-N-phenyl-4,5,6,7-tetrahydro-1H-indole-3-carboxamide hydrochloride::US9765056, Example 113
SMILES Oc1ccc(cc1)N(C(=O)c1cn(c2CCCCc12)-c1cc2OCOc2cc1C(=O)N1Cc2ccccc2C[C@H]1CN1CCOCC1)c1ccccc1
InChI Key InChIKey=UYLDTJKIOUOXLI-XIFFEERXSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 341060
Affinity DataIC50: 19.2nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair