BDBM341060 N-(4-Hydroxyphenyl)-1-(6-{[(3S)-3-(morpholin-4-ylmethyl)-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}-1,3-benzodioxol-5-yl)-N-phenyl-4,5,6,7-tetrahydro-1H-indole-3-carboxamide hydrochloride::US9765056, Example 113

SMILES Oc1ccc(cc1)N(C(=O)c1cn(c2CCCCc12)-c1cc2OCOc2cc1C(=O)N1Cc2ccccc2C[C@H]1CN1CCOCC1)c1ccccc1

InChI Key InChIKey=UYLDTJKIOUOXLI-XIFFEERXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341060   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM341060(N-(4-Hydroxyphenyl)-1-(6-{[(3S)-3-(morpholin-4-ylm...)
Affinity DataIC50:  19.2nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent