BDBM341094 1-{6-[(3S)-3-(Aminomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl]-2-(2-methylpropyl)-2H-1,3-benzodioxol-5-yl}-N-(4-hydroxyphenyl)-N-phenyl-1H-indole-3-carboxamide::US9765056, Example 158
SMILES CC(C)CC1Oc2cc(C(=O)N3Cc4ccccc4C[C@H]3CN)c(cc2O1)-n1cc(C(=O)N(c2ccccc2)c2ccc(O)cc2)c2ccccc12
InChI Key InChIKey=IJYJOGKLBRIZRK-IROIYFLTSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 341094
Affinity DataIC50: 54.1nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair