BDBM341096 N-(4-Hydroxyphenyl)-1-{2-[(3S)-3-[(4-methylpiperazin-1-yl)methyl]-1,2,3,4-tetrahydroisoquinoline-2-carbonyl]-4-[2-(phenylsulphanyl)acetamido]phenyl}-N-phenyl-1H-indole-3-carboxamide::US9765056, Example 163
SMILES CN1CCN(C[C@@H]2Cc3ccccc3CN2C(=O)c2cc(NC(=O)CSc3ccccc3)ccc2-n2cc(C(=O)N(c3ccccc3)c3ccc(O)cc3)c3ccccc23)CC1
InChI Key InChIKey=GFIUMPPRQOJEDJ-RWYGWLOXSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 341096
Affinity DataIC50: 22.8nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair