BDBM341107 1-{2-[(3S)-3-[(Dimethylamino)methyl]-1,2,3,4-tetrahydroisoquinoline-2-carbonyl]-5-methoxyphenyl}-N-(4-hydroxyphenyl)-N-phenyl-1H-indole-3-carboxamide::US9765056, Example 175

SMILES COc1ccc(C(=O)N2Cc3ccccc3C[C@H]2CN(C)C)c(c1)-n1cc(C(=O)N(c2ccccc2)c2ccc(O)cc2)c2ccccc12

InChI Key InChIKey=KSHXXILGTYIWRP-YTTGMZPUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341107   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
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US Patent
LigandPNGBDBM341107(1-{2-[(3S)-3-[(Dimethylamino)methyl]-1,2,3,4-tetra...)
Affinity DataIC50:  25.1nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent