BDBM341107 1-{2-[(3S)-3-[(Dimethylamino)methyl]-1,2,3,4-tetrahydroisoquinoline-2-carbonyl]-5-methoxyphenyl}-N-(4-hydroxyphenyl)-N-phenyl-1H-indole-3-carboxamide::US9765056, Example 175
SMILES COc1ccc(C(=O)N2Cc3ccccc3C[C@H]2CN(C)C)c(c1)-n1cc(C(=O)N(c2ccccc2)c2ccc(O)cc2)c2ccccc12
InChI Key InChIKey=KSHXXILGTYIWRP-YTTGMZPUSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 341107
Affinity DataIC50: 25.1nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair