BDBM341126 1-{4-Hydroxy-5-methoxy-2-[(3S)-3-[(4-methylpiperazin-1-yl)methyl]-1,2,3,4-tetrahydroisoquinoline-2-carbonyl]phenyl}-N-(1H-indol-5-yl)-N-phenyl-1H-indole-3-carboxamide::US9765056, Example 198
SMILES COc1cc(c(cc1O)C(=O)N1Cc2ccccc2C[C@H]1CN1CCN(C)CC1)-n1cc(C(=O)N(c2ccccc2)c2ccc3[nH]ccc3c2)c2ccccc12
InChI Key InChIKey=GPYIKLBRTXFTJU-BHVANESWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 341126
Affinity DataIC50: 3.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair