BDBM341202 (S)-2,4-diamino-6-((1-(5-(3-hydroxy-2-(hydroxymethyl)-2-methylpropoxy)-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile ::US9765060, Compound 29
SMILES C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2cccc(OCC(C)(CO)CO)c2c(=O)n1-c1ccccc1
InChI Key InChIKey=UOANVUBBOCFHED-HNNXBMFYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 341202
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 220nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair