BDBM341279 (S)-4-amino-6-((1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)amino)-2-fluoropyrimidine-5-carbonitrile::US9765060, Compound 106

SMILES C[C@H](Nc1nc(F)nc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1

InChI Key InChIKey=ZOCVIIWPJLLOSN-NSHDSACASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341279   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM341279((S)-4-amino-6-((1-(5-chloro-4-oxo-3-phenyl-3,4-dih...)
Affinity DataIC50:  0.800nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent