BDBM341309 2-[4-(5-Chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-4-methoxy-N-[3-(morpholin-4-ylmethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]butanamide (racemate)::US9765070, Example 26

SMILES COCCC(C(=O)Nc1ccc2nnc(CN3CCOCC3)n2c1)n1cc(OC)c(cc1=O)-c1cc(Cl)ccc1C#N

InChI Key InChIKey=UJSFGKKVMPMPBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 341309   

TargetPlasma kallikrein(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM341309(2-[4-(5-Chloro-2-cyanophenyl)-5-methoxy-2-oxopyrid...)
Affinity DataIC50:  12nMAssay Description:Test substances are dissolved in dimethyl sulphoxide and serially diluted in dimethyl sulphoxide (3000 μM to 0.0078 μM; resulting final con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM341309(2-[4-(5-Chloro-2-cyanophenyl)-5-methoxy-2-oxopyrid...)
Affinity DataIC50:  24nMAssay Description:Test substances are dissolved in dimethyl sulphoxide and serially diluted in dimethyl sulphoxide (3000 μM to 0.0078 μM; resulting final con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent