BDBM34153 CHEMBL476006::indenylsulfonamide, 14
SMILES CN(C)CCC1=C(C)Cc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12
InChI Key InChIKey=SLAAJLIHBBZSNF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 34153
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nM ΔG°: -11.8kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universitat De Barcelona
Curated by ChEMBL
Universitat De Barcelona
Curated by ChEMBL
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human 5HT2C receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Universitat De Barcelona
Curated by ChEMBL
Universitat De Barcelona
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human SERTMore data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Agonist activity at human 5HT6 receptor expressed in HEK293F cells assessed as stimulation of cAMP level after 30 mins by HTRF assay Inhibition of ra...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human adrenergic alpha2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universitat De Barcelona
Curated by ChEMBL
Universitat De Barcelona
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human 5HT1A receptorMore data for this Ligand-Target Pair