BDBM341781 1,3-difluoro-2-(((1,1,1,3,3,3-hexafluoro-2-(4-(1-((4-fluorophenyl)sulfonyl)cyclopent-3-en-1-yl)phenyl)propan-2-yl)oxy)methyl)benzene::US9771320, Example 18

SMILES Fc1ccc(cc1)S(=O)(=O)C1(CC=CC1)c1ccc(cc1)C(OCc1c(F)cccc1F)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=JMQCCQDLQCZUCV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341781   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM341781(1,3-difluoro-2-(((1,1,1,3,3,3-hexafluoro-2-(4-(1-(...)
Affinity DataIC50:  40nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintilla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent