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BDBM341826 US9771320, Example 60

SMILES: Fc1ccc(cc1)S(=O)(=O)C1(CCCC1)c1ccc(cc1)C(OCc1ccccc1C#N)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=SXDNMIOVAAUQPF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341826   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM341826
PNG
(US9771320, Example 60)
Show SMILES Fc1ccc(cc1)S(=O)(=O)C1(CCCC1)c1ccc(cc1)C(OCc1ccccc1C#N)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C28H22F7NO3S/c29-23-11-13-24(14-12-23)40(37,38)25(15-3-4-16-25)21-7-9-22(10-8-21)26(27(30,31)32,28(33,34)35)39-18-20-6-2-1-5-19(20)17-36/h1-2,5-14H,3-4,15-16,18H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 21n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintilla...


US Patent US9771320 (2017)

More data for this
Ligand-Target Pair