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BDBM342071 US9771320, Example 305

SMILES: Fc1ccc(cc1)S(=O)(=O)[C@@]1(C[C@@H](C1)NC(=O)Cc1ccncc1)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=XVEDPMBWNAHRCL-UHGJSFDGSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342071   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM342071
PNG
(US9771320, Example 305)
Show SMILES Fc1ccc(cc1)S(=O)(=O)[C@@]1(C[C@@H](C1)NC(=O)Cc1ccncc1)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C26H20F8N2O3S/c27-19-5-7-21(8-6-19)40(38,39)23(14-20(15-23)36-22(37)13-16-9-11-35-12-10-16)17-1-3-18(4-2-17)24(28,25(29,30)31)26(32,33)34/h1-12,20H,13-15H2,(H,36,37)/t20-,23+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 25n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintilla...


US Patent US9771320 (2017)

More data for this
Ligand-Target Pair