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BDBM342097 US9771320, Example 331

SMILES: Fc1ccc(cc1)S(=O)(=O)[C@]1(CC[C@H](C1)NC(=O)Cc1ccncc1)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=WDTVSXLWNMIVQB-QPPBQGQZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342097   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM342097
PNG
(US9771320, Example 331)
Show SMILES Fc1ccc(cc1)S(=O)(=O)[C@]1(CC[C@H](C1)NC(=O)Cc1ccncc1)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C27H22F8N2O3S/c28-20-5-7-22(8-6-20)41(39,40)24(12-9-21(16-24)37-23(38)15-17-10-13-36-14-11-17)18-1-3-19(4-2-18)25(29,26(30,31)32)27(33,34)35/h1-8,10-11,13-14,21H,9,12,15-16H2,(H,37,38)/t21-,24+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 40n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintilla...


US Patent US9771320 (2017)

More data for this
Ligand-Target Pair