BDBM342103 1-(3-(tert-Butyl)-1-methyl-1H-pyrazol-5-yl)-3-(4-((2-((3-(cyclopropylsulfonyl)-5-methoxy-phenyl)amino)pyrimidin-4-yl)oxy)naphthalen-1-yl)urea::US9771353, Example 3
SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4C)C(C)(C)C)c4ccccc34)n2)cc(c1)S(=O)(=O)C1CC1
InChI Key InChIKey=LUOYPPQEEBEDSR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 342103
Affinity DataIC50: 1.94E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3-alpha enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:p38 MAPKγ: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashio...More data for this Ligand-Target Pair