BDBM342122 N-((4-(3-chlorophenyl)-2-(trifluoromethyl)thiazol-5-yl)methyl)-2-(6-((2-hydroxyethyl)amino)pyridin-3-yl)propanamide::US9771359, EX-14::US9771359, EX-15::US9771359, EX-16

SMILES CC(C(=O)NCc1sc(nc1-c1cccc(Cl)c1)C(F)(F)F)c1ccc(NCCO)nc1

InChI Key InChIKey=MSZOPURSBBDTFC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 342122   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Medifron Dbt

US Patent
LigandPNGBDBM342122(N-((4-(3-chlorophenyl)-2-(trifluoromethyl)thiazol-...)
Affinity DataKi:  0.400nMAssay Description:The FLIPR protocol consists of 2 substance additions during a kinetic measurement. First the compounds to be tested (5 μM) are pipetted onto the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Medifron Dbt

US Patent
LigandPNGBDBM342122(N-((4-(3-chlorophenyl)-2-(trifluoromethyl)thiazol-...)
Affinity DataKi:  0.700nMAssay Description:The FLIPR protocol consists of 2 substance additions during a kinetic measurement. First the compounds to be tested (5 μM) are pipetted onto the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Medifron Dbt

US Patent
LigandPNGBDBM342122(N-((4-(3-chlorophenyl)-2-(trifluoromethyl)thiazol-...)
Affinity DataKi:  41.9nMAssay Description:The FLIPR protocol consists of 2 substance additions during a kinetic measurement. First the compounds to be tested (5 μM) are pipetted onto the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent