BDBM342447 N-{2-[(4aR,6R,8aR)-2- amino-6-(trifluoromethyl)- 4,4a,5,6-tetrahydropyrano [3,4-d][1,3]oxazin-8a(8H)-yl]- 1,3-thiazol-4-yl}-5- (difluoromethoxy)-3-methyl pyrazine-2-carboxamide::US9771379, Example 22
SMILES Cc1nc(OC(F)F)cnc1C(=O)Nc1csc(n1)[C@]12CO[C@H](C[C@H]1COC(N)=N2)C(F)(F)F
InChI Key InChIKey=KZSWBENUZHVEIJ-BTKFHORUSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 342447
Affinity DataIC50: 13nMAssay Description:The BACE1 binding assay measured beta-site amyloid precursor protein-cleaving enzyme (BACE) binding as a decrease in the counts of radioligand bound ...More data for this Ligand-Target Pair