BDBM342510 3-Ethyl-1-phenyl-6-(3,4,5,6-tetrahydro-2H-[1,4′]bipyridinyl-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol::US9771375, Example 92

SMILES CCc1nn(-c2ccccc2)c2nc(nc(O)c12)C1CCN(CC1)c1ccncc1

InChI Key InChIKey=JFVCWEQHUHVPED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342510   

TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM342510(3-Ethyl-1-phenyl-6-(3,4,5,6-tetrahydro-2H-[1,4R...)
Affinity DataIC50:  1.67E+3nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent