BDBM342613 3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1-yl)-4-phenoxy-N-(tetrahydrofuran-2-ylmethyl)benzamide::US9776990, Example 56

SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1cc(ccc1Oc1ccccc1)C(=O)NCC1CCCO1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342613   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM342613(3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1...)
Affinity DataKi:  68nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM342613(3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1...)
Affinity DataKi:  653nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent