BDBM343321 (S)-4-(4,6-dimethylpyridin-2-yl)-N-(2-(3-fluoropyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-methyl-1H-pyrazole-5-carboxamide::US9777000, Example 4.2::US9777000, Example 4.20
SMILES Cc1cc(C)nc(c1)-c1cnn(C)c1C(=O)Nc1ccn2nc(nc2c1)N1CC[C@H](F)C1
InChI Key InChIKey=NXSIXHNWYWVWOT-HNNXBMFYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 343321
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Mochida Pharmaceutical
US Patent
Mochida Pharmaceutical
US Patent
Affinity DataIC50: <5nMAssay Description:IMAP TR-FRET Phosphodiersterase Evaluation Assay Kit (Molecular Device) was used for the measurement. Ten μL of a diluted test compound having e...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Mochida Pharmaceutical
US Patent
Mochida Pharmaceutical
US Patent
Affinity DataIC50: <5nMAssay Description:IMAP TR-FRET Phosphodiersterase Evaluation Assay Kit (Molecular Device) was used for the measurement. Ten μL of a diluted test compound having e...More data for this Ligand-Target Pair