BDBM343345 1-methyl-N-(2-(pyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-4-(6-(trifluoromethyl)pyridin-2-yl)-1H-pyrazole-5-carboxamide::US9777000, Example 4.27

SMILES Cn1ncc(c1C(=O)Nc1ccn2nc(nc2c1)N1CCCC1)-c1cccc(n1)C(F)(F)F

InChI Key InChIKey=IAMHRPZVTBCXGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 343345   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Mochida Pharmaceutical

US Patent
LigandPNGBDBM343345(1-methyl-N-(2-(pyrrolidin-1-yl)-[1,2,4]triazolo[1,...)
Affinity DataIC50: <5nMAssay Description:IMAP TR-FRET Phosphodiersterase Evaluation Assay Kit (Molecular Device) was used for the measurement. Ten μL of a diluted test compound having e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent