BDBM343677 3-(1-Benzofuran-2-yl)-6-{2-[(3R)-morpholin-3-yl]ethoxy}imidazo[1,2-b]pyridazine::US9777004, 8

SMILES C(C[C@@H]1COCCN1)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1

InChI Key InChIKey=FCVZAGHPGIACKM-OAHLLOKOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 343677   

TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM343677(3-(1-Benzofuran-2-yl)-6-{2-[(3R)-morpholin-3-yl]et...)
Affinity DataIC50:  20nMAssay Description:For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM343677(3-(1-Benzofuran-2-yl)-6-{2-[(3R)-morpholin-3-yl]et...)
Affinity DataIC50:  6nMAssay Description:For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent