BDBM343699 3-(5-Fluoro-1-benzofuran-2-yl)-6-[(2R)-morpholin-2-ylmethoxy]imidazo[1,2-b]-pyridazine::US9777004, 34

SMILES Fc1ccc2oc(cc2c1)-c1cnc2ccc(OC[C@H]3CNCCO3)nn12

InChI Key InChIKey=XZVKEWCFFKMHPW-CQSZACIVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 343699   

TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM343699(3-(5-Fluoro-1-benzofuran-2-yl)-6-[(2R)-morpholin-2...)
Affinity DataIC50:  11nMAssay Description:For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM343699(3-(5-Fluoro-1-benzofuran-2-yl)-6-[(2R)-morpholin-2...)
Affinity DataIC50:  10nMAssay Description:For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent