BDBM344356 (1 S,3R*)-1-(3-Fluoro-2-methylphenyl)-3-(5-fluoro-6-(2-(pyrrolidin-1-yl)ethoxy)pyridin-3-yl)-N-hydroxycyclopentanecarboxamide::US9783488, Example 48

SMILES Cc1c(F)cccc1[C@@]1(CC[C@H](C1)c1cnc(OCCN2CCCC2)c(F)c1)C(=O)NO

InChI Key InChIKey=FRFMGCFWJFUXBT-OSPHWJPCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344356   

TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM344356((1 S,3R*)-1-(3-Fluoro-2-methylphenyl)-3-(5-fluoro-...)
Affinity DataIC50:  320nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent