BDBM344396 (E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(morpholin-4-yl)propoxy)quinoline-4-yloxy)phenyl)-N4-(3-allyl-2-hydroxybenzaldehyde)thiosemicarbazone::US9783499, Example 35

SMILES COc1cc2c(Oc3ccc(cc3F)N(\N=C\c3cccc(CC=C)c3O)C(N)=S)ccnc2cc1OCCCN1CCOCC1

InChI Key InChIKey=UTMAXCHEGLNVNN-NNLKUIAGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344396   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344396((E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(morpholin-4-yl...)
Affinity DataIC50:  12nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent