BDBM344436 (S or R)-ethyl 3-((S)-4-((4-fluoro- 3- (trifluoromethyl)phenyl)sulfonyl)- 6-((((1,1,1-trifluoro-2- methylpropan-2- yl)oxy)carbonyl)amino)-3,4- dihydro-2H-benzo[b][1,4]oxazin- 2-yl)-2-methylpropanoate::US9783511, 3G

SMILES CCOC(=O)[C@H](C)C[C@H]1CN(c2cc(NC(=O)OC(C)(C)C(F)(F)F)ccc2O1)S(=O)(=O)c1ccc(F)c(c1)C(F)(F)F

InChI Key InChIKey=CLVFSWROAOPIPK-ZBFHGGJFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344436   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM344436((S or R)-ethyl 3-((S)-4-((4-fluoro- 3- (trifluorom...)
Affinity DataIC50:  8nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent