BDBM344491 (S)-4-((2-(2-carboxyethyl)- 6-((((1,1,1-trifluoro-2- methylpropan-2- yl)oxy)carbonyl)amino)- 2H-benzo[b][1,4]oxazin- 4(3H)-yl)sulfonyl)-1-(2,2- difluoroethyl)-3-ethoxy- 1H-pyrazole::US9783511, 6AR

SMILES CCOc1nn(CC(F)F)cc1S(=O)(=O)N1C[C@H](CCC(O)=O)Oc2ccc(NC(=O)OC(C)(C)C(F)(F)F)cc12

InChI Key InChIKey=RVFMVWWADJTTMX-AWEZNQCLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344491   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM344491((S)-4-((2-(2-carboxyethyl)- 6-((((1,1,1-trifluoro-...)
Affinity DataIC50:  4.86nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent