BDBM344532 3-(4-[(3-ethoxy-1-ethyl-1H- pyrazol-4-yl)sulfonyl]-6- {[(2,2,2-trifluoro-1,1- dimethylethoxy)carbonyl] amino}-3,4-dihydro-2H-1,4- benzoxazin-2-yl)propanoic acid::US9783511, 6CB

SMILES CCOc1nn(CC)cc1S(=O)(=O)N1C[C@H](CCC(O)=O)Oc2ccc(NC(=O)OC(C)(C)C(F)(F)F)cc12

InChI Key InChIKey=NJGNJCAWCGKVNZ-HNNXBMFYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344532   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM344532(3-(4-[(3-ethoxy-1-ethyl-1H- pyrazol-4-yl)sulfonyl]...)
Affinity DataIC50:  6.96nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent