BDBM344719 1-{2-[(2S)-2-ethylpyrrolidin-1-yl]-2-oxoethyl}-3-[1-(2-fluorophenyl)-1H-indazol-4-yl]imidazolidin-2-one::US9783527, Example 21

SMILES CC[C@H]1CCCN1C(=O)CN1CCN(C1=O)c1cccc2n(ncc12)-c1ccccc1F

InChI Key InChIKey=SATBEMFZJZCMMB-KRWDZBQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344719   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344719(1-{2-[(2S)-2-ethylpyrrolidin-1-yl]-2-oxoethyl}-3-[...)
Affinity DataIC50:  314nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent