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BDBM34475 9-bromanyl-4-oxidanyl-6H-chromeno[2,3-b]indol-3-one::9-bromo-4-hydroxy-6H-[1]benzopyrano[2,3-b]indol-3-one::9-bromo-4-hydroxy-6H-chromen[2,3-b]indol-3-one::9-bromo-4-hydroxy-6H-chromeno[2,3-b]indol-3-one::9-bromochromeno[2,3-b]indole-3,4-diol::MLS000049296::SMR000075134::cid_976141

SMILES: Oc1c2oc3[nH]c4ccc(Br)cc4c3cc2ccc1=O

InChI Key: InChIKey=NKSLAYNUDADNIW-UHFFFAOYSA-N

Data: 5 IC50  5 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 34475   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gag-Pol polyprotein


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM34475
PNG
(9-bromanyl-4-oxidanyl-6H-chromeno[2,3-b]indol-3-on...)
Show SMILES Oc1c2oc3[nH]c4ccc(Br)cc4c3cc2ccc1=O
Show InChI InChI=1S/C15H8BrNO3/c16-8-2-3-11-9(6-8)10-5-7-1-4-12(18)13(19)14(7)20-15(10)17-11/h1-6,17,19H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PCBioAssay
n/an/a 1.49E+3n/an/an/an/a8.023



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
A fluorescence resonance energy transfer assay is developed in 96-well and 384-well microplate formats with robotic manipulation to enable high-throu...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H70D5W
More data for this
Ligand-Target Pair
MPI protein


(Homo sapiens)
BDBM34475
PNG
(9-bromanyl-4-oxidanyl-6H-chromeno[2,3-b]indol-3-on...)
Show SMILES Oc1c2oc3[nH]c4ccc(Br)cc4c3cc2ccc1=O
Show InChI InChI=1S/C15H8BrNO3/c16-8-2-3-11-9(6-8)10-5-7-1-4-12(18)13(19)14(7)20-15(10)17-11/h1-6,17,19H
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UniProtKB/SwissProt

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PC sid
UniChem
PCBioAssay
n/an/a 3.00E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2CF9NFM
More data for this
Ligand-Target Pair
Estradiol receptor beta (ERβ)


(Homo sapiens (Human))
BDBM34475
PNG
(9-bromanyl-4-oxidanyl-6H-chromeno[2,3-b]indol-3-on...)
Show SMILES Oc1c2oc3[nH]c4ccc(Br)cc4c3cc2ccc1=O
Show InChI InChI=1S/C15H8BrNO3/c16-8-2-3-11-9(6-8)10-5-7-1-4-12(18)13(19)14(7)20-15(10)17-11/h1-6,17,19H
UniProtKB/SwissProt

GoogleScholar
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PC sid
UniChem
PCBioAssay
n/an/a 5.38E+3n/an/an/an/an/an/a



Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay


Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2CF9NHH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (human))
BDBM34475
PNG
(9-bromanyl-4-oxidanyl-6H-chromeno[2,3-b]indol-3-on...)
Show SMILES Oc1c2oc3[nH]c4ccc(Br)cc4c3cc2ccc1=O
Show InChI InChI=1S/C15H8BrNO3/c16-8-2-3-11-9(6-8)10-5-7-1-4-12(18)13(19)14(7)20-15(10)17-11/h1-6,17,19H
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
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PC cid
PC sid
UniChem
PCBioAssay
n/an/a>448n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2J67FCM
More data for this
Ligand-Target Pair
Alpi


(Rattus norvegicus (Rat))
BDBM34475
PNG
(9-bromanyl-4-oxidanyl-6H-chromeno[2,3-b]indol-3-on...)
Show SMILES Oc1c2oc3[nH]c4ccc(Br)cc4c3cc2ccc1=O
Show InChI InChI=1S/C15H8BrNO3/c16-8-2-3-11-9(6-8)10-5-7-1-4-12(18)13(19)14(7)20-15(10)17-11/h1-6,17,19H
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a 2.21E+4n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2J38R0R
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase 33


(Homo sapiens)
BDBM34475
PNG
(9-bromanyl-4-oxidanyl-6H-chromeno[2,3-b]indol-3-on...)
Show SMILES Oc1c2oc3[nH]c4ccc(Br)cc4c3cc2ccc1=O
Show InChI InChI=1S/C15H8BrNO3/c16-8-2-3-11-9(6-8)10-5-7-1-4-12(18)13(19)14(7)20-15(10)17-11/h1-6,17,19H
KEGG

UniProtKB/SwissProt

GoogleScholar
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PC sid
UniChem
PCBioAssay
n/an/an/an/a 4.01E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: STK33 Kinase, Non-ATP Competitive Inhibitor Assay Overview: Purified STK33 Kinase is preincubated with potential inhibitors and allowed to ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B27SRF
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Homo sapiens)
BDBM34475
PNG
(9-bromanyl-4-oxidanyl-6H-chromeno[2,3-b]indol-3-on...)
Show SMILES Oc1c2oc3[nH]c4ccc(Br)cc4c3cc2ccc1=O
Show InChI InChI=1S/C15H8BrNO3/c16-8-2-3-11-9(6-8)10-5-7-1-4-12(18)13(19)14(7)20-15(10)17-11/h1-6,17,19H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a 2.12E+4n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q29G5K8R
More data for this
Ligand-Target Pair
Alkaline phosphatase placental-like


(Homo sapiens)
BDBM34475
PNG
(9-bromanyl-4-oxidanyl-6H-chromeno[2,3-b]indol-3-on...)
Show SMILES Oc1c2oc3[nH]c4ccc(Br)cc4c3cc2ccc1=O
Show InChI InChI=1S/C15H8BrNO3/c16-8-2-3-11-9(6-8)10-5-7-1-4-12(18)13(19)14(7)20-15(10)17-11/h1-6,17,19H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
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PC sid
UniChem
PCBioAssay
n/an/an/an/a 2.41E+4n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2SJ1J25
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM34475
PNG
(9-bromanyl-4-oxidanyl-6H-chromeno[2,3-b]indol-3-on...)
Show SMILES Oc1c2oc3[nH]c4ccc(Br)cc4c3cc2ccc1=O
Show InChI InChI=1S/C15H8BrNO3/c16-8-2-3-11-9(6-8)10-5-7-1-4-12(18)13(19)14(7)20-15(10)17-11/h1-6,17,19H
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
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PC sid
UniChem
PCBioAssay
n/an/an/an/a 2.40E+4n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2J101NV
More data for this
Ligand-Target Pair
Bcl-2-like protein 1


(Homo sapiens)
BDBM34475
PNG
(9-bromanyl-4-oxidanyl-6H-chromeno[2,3-b]indol-3-on...)
Show SMILES Oc1c2oc3[nH]c4ccc(Br)cc4c3cc2ccc1=O
Show InChI InChI=1S/C15H8BrNO3/c16-8-2-3-11-9(6-8)10-5-7-1-4-12(18)13(19)14(7)20-15(10)17-11/h1-6,17,19H
PDB
MMDB

NCI pathway
Reactome pathway
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UniProtKB/SwissProt

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UniChem
PCBioAssay
n/an/a 1.09E+5n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DF6PNW
More data for this
Ligand-Target Pair