BDBM345038 N-(3,3-difluorocyclohexyl)-::N-(3,3-difluorocyclohexyl)-2-{3-[1-(2-fluorophenyl)-1H-indazol-4-yl]-2-oxoimidazolidin-1-yl}acetamide::US9783527, Example 340

SMILES Fc1ccccc1-n1ncc2c(cccc12)N1CCN(CC(=O)NC2CCCC(F)(F)C2)C1=O

InChI Key InChIKey=BPNDYLQZAFWYLN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 345038   

TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM345038(N-(3,3-difluorocyclohexyl)- | N-(3,3-difluorocyclo...)
Affinity DataIC50:  637nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM345038(N-(3,3-difluorocyclohexyl)- | N-(3,3-difluorocyclo...)
Affinity DataIC50:  2.64E+3nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent