BDBM345192 (R)-2-((S)-3,3-Dimethyl-2-((S)-2- (methylamino)propanamido) butanoyl)-6-((4-(((3S,5S)-1-((S)- 3,3-dimethyl-2-((5)-2- (methylamino)propanamido) butanoyl)-5-(((R)-1,2,3,4- tetrahydronaphthalen-1- yl)carbamoyl)pyrrolidin-3- yl)carbamoyl)benzyl)oxy)-N-((R)- 1,2,3,4-tetrahydronaphthalen-1- yl)-1,2,3,4-tetrahydroisoquinoline- 3-carboxamide::US9783573, Example 42
SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H](C[C@H]1C(=O)NC1CCCc2ccccc12)NC(=O)c1ccc(COc2ccc3CN([C@H](Cc3c2)C(=O)NC2CCCc3ccccc23)C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)cc1)C(C)(C)C
InChI Key InChIKey=MHUDJHSFECRQLB-CUTNUHKBSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 345192
TargetBaculoviral IAP repeat-containing protein 2/E3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.30E+3nMAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3/E3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 240nMAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3 (241-356...More data for this Ligand-Target Pair