BDBM345224 (1S,3S*)-3-(2- Cyclopropylbenzo[d]thiazol- 6-yl)-1-(3-fluoro-2- methylphenyl)-N- hydroxycyclopentanecarboxamide::US9783488, Example 77

SMILES Cc1c(F)cccc1[C@@]1(CC[C@@H](C1)c1ccc2nc(sc2c1)C1CC1)C(=O)NO

InChI Key InChIKey=FVSHRAFFHIROGV-HJPURHCSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345224   

TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM345224((1S,3S*)-3-(2- Cyclopropylbenzo[d]thiazol- 6-yl)-1...)
Affinity DataIC50:  310nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent