BDBM345248 (1r,4r)-1-(3-fluoro-2-methylphenyl)-N-hydroxy-4-phenoxycyclohexanecarboxamide::US9783488, Example 101

SMILES Cc1c(F)cccc1[C@@]1(CC[C@@H](CC1)Oc1ccccc1)C(=O)NO

InChI Key InChIKey=ADVKDBSKBQIPTJ-UKIBZPOASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345248   

TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM345248((1r,4r)-1-(3-fluoro-2-methylphenyl)-N-hydroxy-4-ph...)
Affinity DataIC50:  680nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent