BDBM345295 1-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxyphenyl)pyrazol-3- yl]methoxy]cyclobutanecarboxylic acid. 1HNMR (CDCl3): $#948; 1.78-1.85 (m 1H), 1.95-2.04 (m, 2H), 2.18-2.25 (m, 1H), 3.09-3.14 (m, 1H), 3.66 (s, 3H), 4.27-4.32 (m, 1H), 4.55-4.65 (dd, 2H), 5.43 (s, 2H), 6.44 (s, 1H), 6.73-6.91 (m, 4H), 7.17-7.34 (m 4).::US10202350, Example 41::US10214492, Example 41::US11292767, Example 41::US11724989, Example 41
SMILES COc1cccc(c1)-c1cc(COC2(CCC2)C(O)=O)nn1Cc1ccccc1Cl
InChI Key InChIKey=AMBDDVHEOJZXJJ-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 345295
Affinity DataIC50: 55nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair