BDBM345338 1-cyclobutyl-4-[1-[4-(4-methoxyphenyl)phe-nyl]sulfonyl-4,5-dihydroimidazol-2-yl]piperazine::US10202354, Example 3

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N1CCN=C1N1CCN(CC1)C1CCC1

InChI Key InChIKey=ONFFYBIIQNAOCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345338   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345338(1-cyclobutyl-4-[1-[4-(4-methoxyphenyl)phe-nyl]sulf...)
Affinity DataIC50:  0.0800nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent