BDBM345372 1-cyclobutyl-4-[1-(4-isopropylphenyl)sulfonyl-4,5-dihydroimidazol-2-yl]-2-methyl-::US10202354, Example 37

SMILES CC(C)c1ccc(cc1)S(=O)(=O)N1CCN=C1N1CCN(C2CCC2)[C@@H](C)C1

InChI Key InChIKey=DGZAKXCWCBQAJB-KRWDZBQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345372   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345372(1-cyclobutyl-4-[1-(4-isopropylphenyl)sulfonyl-4,5-...)
Affinity DataIC50:  0.689nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent